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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T4068 | E6446 dihydrochloride | TLR | |
E6446 dihydrochloride is a novel synthetic antagonist for nucleic acid-sensing TLRs; potently suppressed DNA stimulation of HEK:TLR9 cells with IC50 of 10 nM. | |||
T4206 | E6446 | TLR | |
E6446 inhibits Toll-like receptor (TLR)7 and 9 signaling. E6446 works in a variety of human and mouse cell types and inhibits DNA-TLR9 interaction in vitro. When administered to mice, this compound suppress responses to ... |